![Picture](/uploads/2/0/6/1/20610398/2561008.jpg?322)
Phenothiazines
History: Multiple people were involved in the discovery of phenothiazines, which are a group of antipsychotic drugs with special properties when used with mental patients. Credit is typically given to Henri Laborit, a French surgeon. He discovered that the most effective type of phenothiazine, named chlorpromazine did not cause fatigue or a loss of consciousness by itself, but it did make patients calm and emotionally relaxed. He encouraged psychiatric colleagues to experiment with the drug on their patients. The first report proved that not only were the patients calmed, but the drug also appeared to act on the psychosis process itself. As these drugs continued to progress they received many names. They were commonly referred to as "tranquilizers," which was unfortunate as the term tranquilizer implies sedation. This group of drugs later became known as antipsychotics, reflecting their capability to reduce psychotic symptoms without producing sedation or drowsiness.[1]
Modes of intake: Phenothiazines are taken orally in the form of pills.[1]
Immediate effects: Phenothiazines do not create drug dependencies but have a wide range of side effects. These symptoms range from skin rashes, facial tics and significant weight gain. They cause fatigue and effects that are describes as pleasant.[2]
Long term effects: Drug dependence is not an issue with phenothiazines. Over time, they can decrease sexual interest and lower performance in males. Women's menstruation cycles may be interfered with.[2]
Medical Applications: Phenothiazines are used to treat patients suffering from schizophrenia.They work by blocking dopamine receptors.[2]
Misuse and Abuse: Phenothiazines and antipsychotics are not misused.[2]
Picture [5]
History: Multiple people were involved in the discovery of phenothiazines, which are a group of antipsychotic drugs with special properties when used with mental patients. Credit is typically given to Henri Laborit, a French surgeon. He discovered that the most effective type of phenothiazine, named chlorpromazine did not cause fatigue or a loss of consciousness by itself, but it did make patients calm and emotionally relaxed. He encouraged psychiatric colleagues to experiment with the drug on their patients. The first report proved that not only were the patients calmed, but the drug also appeared to act on the psychosis process itself. As these drugs continued to progress they received many names. They were commonly referred to as "tranquilizers," which was unfortunate as the term tranquilizer implies sedation. This group of drugs later became known as antipsychotics, reflecting their capability to reduce psychotic symptoms without producing sedation or drowsiness.[1]
Modes of intake: Phenothiazines are taken orally in the form of pills.[1]
Immediate effects: Phenothiazines do not create drug dependencies but have a wide range of side effects. These symptoms range from skin rashes, facial tics and significant weight gain. They cause fatigue and effects that are describes as pleasant.[2]
Long term effects: Drug dependence is not an issue with phenothiazines. Over time, they can decrease sexual interest and lower performance in males. Women's menstruation cycles may be interfered with.[2]
Medical Applications: Phenothiazines are used to treat patients suffering from schizophrenia.They work by blocking dopamine receptors.[2]
Misuse and Abuse: Phenothiazines and antipsychotics are not misused.[2]
Picture [5]